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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Reboxetine
supplement:
Yohimbine
Research Papers that Mention the Interaction
“This antiallodynic effect of intrathecal reboxetine was blocked by prior administration of yohimbine (&agr;2-adrenoceptor antagonist, 30 &mgr;g) but not by prazosin (&agr;1-adrenoceptor antagonist, 30 &mgr;g) or propranolol (&bgr;-adrenoceptor antagonist, 100 &mgr;g).”
Intrathecal reboxetine suppresses evoked and ongoing neuropathic pain behaviours by restoring spinal noradrenergic inhibitory tone“The adrenergic antagonists yohimbine and phentolamine attenuated to some extent the reboxetine-induced antinociception, implying a minor adrenergic mechanism of antinociception.”
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