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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Quinine
drug:
Tolbutamide
Research Papers that Mention the Interaction
“The action of tolbutamide was mimicked by the general K+ channel blockers TEA (10 mm) and quinine (10 μm).”
Tolbutamide stimulates exocytosis of glucagon by inhibition of a mitochondrial‐like ATP‐sensitive K+ (KATP) conductance in rat pancreatic A‐cells“4 In the presence of quinine (10 μm), D600 (50 μm), or tetraethylammonium (20 mm), the secondary increase in 86Rb following tolbutamide (0.7 mm) removal was totally inhibited.”
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