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Last Updated: 2 years ago
supplement:
Quinine
Research Papers that Mention the Interaction
“The release reaction could be antagonized by phospholipase A2 inhibitors such as quinacrine and quinine , suggesting that THC can stimulate the activity of this enzyme.”
Prostaglandins and Cannabis—VIII. Elevation of Phospholipase A2 Activity by Cannabinoids in Whole Cells and Subcellular Preparations“Here we provide evidence that the cannabinoid agonist, Delta9-tetrahydrocannabinol Delta9-THC ) enhances quinine palatability and the CB1 antagonist/inverse agonist, AM251, reduces sucrose and quinine palatability using the taste reactivity test, which provides a direct measure of palatability independently of appetitive behavior.”
“Regardless of the post-injection interval, Delta9-THC reduced rejection of quinine.”
Effect of Δ9-tetrahydrocannabinol on quinine palatability and AM251 on sucrose and quinine palatability using the taste reactivity test“Conversely, the hypothermic effect of Delta(9)-tetrahydrocannabinol was potentiated by the D(2) dopamine receptor agonists (-)-quinpirole (0.025 and 0.500 mg/kg, SC) and (+)-bromocriptine (0.5 and 1 mg/kg, IP).”
“Conversely, Delta(9)-tetrahydrocannabinol antinociceptive effects were potentiated by the dopamine D(2) receptor agonists (-)-quinpirole (0.025 mg/kg, s.c.)”
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