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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“Local perfusion with quinine , a K+ channel blocker, completely blocked the (—)‐sulpiride‐induced increases in DA but did not affect the DA agonist‐induced decreases.”
Effect of Quinine on Autoreceptor‐Regulated Dopamine Release in the Rat Striatum“Pimozide (4mg/kg, ip), L-sulpiride (40mg/kg, ip), SCH 23390 (0.2mg/kg, sc) and alpha-methyl-p-tyrosine (50mg/kg, ip) effectively potentiated the antinociceptive effects of quinine (50mg/kg, ip).”
“On the other hand, pimozide (0.2 mg/kg intraperitoneally), L-sulpiride (40 mg/kg intraperitoneally and SCH 23390 (0.2 mg/kg subcutaneously) potentiated the locomotor depressant effect of high doses of quinine (1-5 mg/kg) intraperitoneally).”
“Pimozide (4 mg/kg intraperitoneally) and L-sulpiride (40 mg/kg intraperitoneally) antagonized both the circling and increase in locomotor activity induced by quinine (0.1 mg/kg intra peritoneally) and D-amphetamine (4 mg/kg intraperitoneally) respectively.”
Some behavioural effects of quinine in mice
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