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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
supplement:
Quinine
drug:
Gentamicin
Research Papers that Mention the Interaction
“The antimalarial drugs chloroquine and the quinine and the aminoglycoside antibiotics gentamicin and neomycin all of which, like Zn2+, have been shown to block neuromuscular transmission, also inhibited the enzyme.”
Inhibition of phosphatidylinositol phosphodiesterase activity in skeletal muscle by metal ions and drugs which block neuromuscular transmission.“Pharmacologic blockade of MET channels with curare or quinine , but not concanavalin A or dynosore, prevented hair cell loss when challenged with gentamicin for up to 96 hours.”
Functional Hair Cell Mechanotransducer Channels Are Required for Aminoglycoside Ototoxicity“Fifteen-minute gentamicin (10 microM) uptake was inhibited by 1 mM of the organic cations cimetidine (61.0%), quinidine (73.5%), quinine (68.6%), and verapamil (61.5%).”
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