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Last Updated: 2 years ago

Possible Interaction: Quinidine and Vinblastine

supplement:

Quinidine

Research Papers that Mention the Interaction

Quinidine is known to inhibit p-glycoprotein and enhance the activity of vinblastine against cultured renal carcinoma cells.
American journal of clinical oncology  •  1995  |  View Paper
Like verapamil (10 μM) itself, three of the other …, namely, S9788 (4 μM), flunarizine (20 μM) and quinidine (30 μM), resulted in … 3-fold sensitization of vinblastine against the parental CEM cells, and comparable effects were noted in … CEM/VM-1 cells, which were not cross-resistant to vinblastine.
Cancer Chemotherapy and Pharmacology  •  2004  |  View Paper
This fraction inhibited the efflux of vinblastine from MDR cells, and also inhibited the photoaffinity labeling of P-gp with azidopine as effectively as vinblastine, quinidine and cepharanthine.
Biochemical and biophysical research communications  •  1990  |  View Paper