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Discover Supplement-Drug Interactions

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Last Updated: 5 months ago

Possible Interaction: Quinidine and Trazodone

supplement:

Quinidine

Research Papers that Mention the Interaction

In contrast to CYP3A4-dependent bioactivation of trazodone itself, formation of M4 was mediated specifically by …-expressed CYP2D6-catalyzing formation of M4 from m-CPP, strong inhibition of formation of M4 by quinidine , a specific … of trazodone and m-CPP with human liver … inhibition of M4 formation by quinidine.
Drug Metabolism and Disposition  •  2008  |  View Paper
Inhibition of CYP2D6 by quinidine and cimetidine increased the cytotoxicity of both trazodone and m-CPP.
Drug research  •  2016  |  View Paper