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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Quinidine and Topotecan

supplement:

Quinidine

Research Papers that Mention the Interaction

In 10 of 11 samples, … multi-drug resistance (Mdr) modulator quinidine altered nuclear daunorubicin (DNR) accumulation and whole-cell TPT accumulation by less than 15%, which suggests that Pgp-mediated effects on drug efflux are insufficient to explain the fourfold range of TPT sensitivities in the colony-forming assays.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology  •  1994  |  View Paper