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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Quinidine
drug:
Tolbutamide
Research Papers that Mention the Interaction
“The probes sulfaphenazole (CYP2C9) and quinidine (CYP2D6) selectively inhibited tolbutamide methylhydroxylation and bufuralol 1'-hydroxylation, respectively.”
Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.“The addition of therapeatic concentrations of salicylic acid, phenylbutazone, and tolbutamide significantly reduced quinidine binding (p < 0.025), but 10 other commonly coadministered drugs did not.”
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