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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Quinidine
drug:
Tetraethylammonium
Research Papers that Mention the Interaction
“The voltage-dependent Po was fitted with the Boltzmann's equation: Po = 1/[1 + exp(V-…/2)zF/RT], with z = 1.2 and V1/2 = -40 mV. Addition of 2 mM tetraethylammonium or … mM quinidine to the bath blocked the activity of … K+ channel in inside-out patches.”
Regulation of the hyperpolarization-activated K+ channel in the lateral membrane of the cortical collecting duct [published erratum appears in J Gen Physiol 1995 Sep;106(3):579]“ Quinidine administration at 75 mg/kg/day for four days reduced tetraethylammonium transport in both young and old.”
“ Quinidine in vitro significantly reduced accumulation of TEA ( tetraethyl ammonium ) and PAH (p-amino hippurate) and inhibited oxygen consumption in renal cortical slices.”
“One is affected by aminopyridines or Sh mutations, a second component is affected by the slo mutation, a third is sensitive to quinidine and one or more additional components are blocked by tetraethylammonium.”
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