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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Quinidine
drug:
Sulfaphenazole
Research Papers that Mention the Interaction
“The addition of quinidine , a selective inhibitor of CYP2D6, along with triacetyloleandomycin and sulphaphenazole produced an additional decrease in the rate of NT formation in all but the PM liver, but did not completely eliminate the reaction.”
Cytochromes P450 mediating the N-demethylation of amitriptyline.“However, in contrast, coincubation with the P450 2C9 inhibitor sulfaphenazole (10 μM) or the P450 2D6 inhibitor quinidine (40 μM) led to a 1.9- and 1.6-fold increase in DPAB-SG production, respectively.”
A Novel Bioactivation Pathway for 2-[2-(2,6-Dichlorophenyl)aminophenyl]ethanoic Acid (Diclofenac) Initiated by Cytochrome P450-Mediated Oxidative Decarboxylation
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