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Discover Supplement-Drug Interactions

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Last Updated: 3 years ago

Possible Interaction: Quinidine and Spironolactone

supplement:

Quinidine

Research Papers that Mention the Interaction

Spironolactone and quinidine , alone and in combination, reduced digoxin systemic, renal, and nonrenal clearances and prolonged digoxin elimination t½. A greater alteration in digoxin kinetics was induced by quinidine than by spironolactone, and an even greater effect resulted from the combination.
Clinical pharmacology and therapeutics  •  1984  |  View Paper