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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
Research Papers that Mention the Interaction
“CONCLUSION By restoring the dome and the APD of the epicardial and midcardial cells action potentials, qu nidine (5 micromol/L) could reduce the marked transmural dispersion of repolarization caused by pin acidil. ”
“ Quinidine (5 micromol/L) effectively prolonged the APD abbreviated by pinacidil , restored or partly restored the dome of transmembrane action potentials of epicardial and midcardial cells but not of endocardial cells (n = 10).”
[Effects of quinidine on pinacidil-induced transmural dispersion of repolarization in canine right ventricular wall].“5 In the presence of … drug concentrations, however, pinacidil decreased the QRS prolongation … by mexiletine (−17%) and quinidine (− 8%), but not that induced by flecainide: this effect was already maximal at the lower concentration … (10 μm) and there was no relationship between pinacidil‐induced JT shortening and QRS changes.”
“6 Flecainide, but not quinidine and mexiletine, antagonized the JT shortening induced by pinacidil ; furthermore, no drug modified the JTp/JT decrease induced by pinacidil.”
“ Quinidine , but not lidocaine and aprindine, prevented VF induced by pinacidil and hypoxia.”
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