Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Quinidine and Moxonidine

supplement:

Quinidine

Research Papers that Mention the Interaction

AIMS To test the hypothesis that the renal clearance of moxonidine decreases when dosed with quinidine.
RESULTS When coadministered, qu nidine si gnificantly increased mox onidine AU C and t1/2 by 11% and 15%, respectively, and decreased CL/F by 10% compared with the control dosing.
The decrease in apparent total clearance of moxonidine with quinidine coadministration was possibly due to metabolic inhibition, though not likely to be clinically significant.
British journal of clinical pharmacology  •  2002  |  View Paper