supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 4 years ago
supplement:
Quinidine
drug:
Metipranolol
Research Papers that Mention the Interaction
“The coadministration of quinidine resulted in a doubling of the area under the plasma concentration—time curve of (±)‐propranolol (530 ± 99 versus 1051 ± 138 ng · hr/ml; p < 0.05) and a reduction in the clearance of (±)‐propranolol from 3087 ± 648 to 1378 ± 173 ml/min (p < 0.05).”
Quinidine reduces clearance of (+)‐propranolol more than (−)‐propranolol through marked reduction in 4‐hydroxylation
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback