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Discover Supplement-Drug Interactions

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Last Updated: 4 months ago

Possible Interaction: Quinidine and Loratadine

supplement:

Quinidine

Research Papers that Mention the Interaction

Quinidine (5 microm), a CYP2D6 inhibitor, inhibited the formation … approximately 20% when added to microsomal incubations of loratadine at concentrations of 7-35 microM. Incubation of loratadine with cDNA-expressed CYP3A4 and CYP2D6 microsomes … formation of DCL with formation rates of 135 and 633 pmol/min/nmol P450, respectively.
Biochemical pharmacology  •  1996  |  View Paper