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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Quinidine and Itraconazole

supplement:

Quinidine

Research Papers that Mention the Interaction

Itraconazole interacts with some but not all of the substrates of CYP3A4; it is therefore important to study the possible interaction of itraconazole with quinidine.
Clinical pharmacology and therapeutics  •  1997  |  View Paper
Concomitant administration of itraconazole reduced quinidine total clearance, partial clearance by 3-hydroxylation and partial clearance by N-oxidation by 61, 84 and 73%, respectively.
British journal of clinical pharmacology  •  1999  |  View Paper