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Discover Supplement-Drug Interactions

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Last Updated: 3 months ago

Possible Interaction: Quinidine and Halofantrine

supplement:

Quinidine

Research Papers that Mention the Interaction

In conclusion, we showed that quinine and quinidine coadministered with HF might inhibit its metabolism resulting in the potentiation of HF-induced cardiotoxicity in patients.
Mefloquine, quinine, quinidine , and ketoconazole used at maximal plasma concentrations inhibited N-debutylhalofantrine formation noncompetitively with Ki values of 70 microM, 49 microM, 62 microM, and 0.05 microM resulting in 7%, 49%, 26%, and 99% inhibition, respectively, in HF metabolism.
Drug metabolism and disposition: the biological fate of chemicals  •  1999  |  View Paper