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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Quinidine
drug:
Dexchlorpheniramine
Research Papers that Mention the Interaction
“… (S)-(+)-chlorpheniramine, … quinidine , an inhibitor of CYP2D6, resulted in an increase in Cmax to 13.94+/-1.51 (P<0.01), a reduction in CLoral to ….01), and a prolongation of elimination half-life from 18.0+/-2.0 h to 29.3+/-2.0 h (P<0.001).”
The roles of CYP2D6 and stereoselectivity in the clinical pharmacokinetics of chlorpheniramine.
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