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Discover Supplement-Drug Interactions
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Last Updated: 4 years ago
supplement:
Quinidine
drug:
Desvenlafaxine
Research Papers that Mention the Interaction
“ Quinidine (QUI) was a … inhibitor of ODV formation with a Ki of 0.04 μM, and paroxetine (PX) was the most potent SSRI at inhibiting ODV formation with … mean Ki value of 0.17 μM. Studies using expressed cytochromes showed that ODV was formed by CYP2C9, −2C19, and −2D6.”
O- and N-demethylation of Venlafaxine In Vitro by Human Liver Microsomes and by Microsomes from cDNA-Transfected Cells: Effect of Metabolic Inhibitors and SSRI Antidepressants
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