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Discover Supplement-Drug Interactions

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Last Updated: 2 years ago

Possible Interaction: Quinidine and Anticholinergic Agents

Research Papers that Mention the Interaction

Quinidine and disopyramide caused minor delays of repolarization, but both were primarily class 1 agents, and in addition had undesirable anticholinergic activity.
European heart journal  •  1985  |  View Paper
The anticholinergic and antiadrenergic actions occur concurrently and are unrelated to the direct action: both of these effects increase in direct relation to the concentration of quinidine.
American heart journal  •  1964  |  View Paper
Hence, the direct blockage of the acetylcholine-activated K+ current by quinidine was considered responsible for the anticholinergic action of this drug.
Naunyn-Schmiedeberg's Archives of Pharmacology  •  2004  |  View Paper