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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Quercetin
drug:
Uridine Triacetate
Research Papers that Mention the Interaction
“Several in vitro and in vivo studies have also shown that quercetin destabilizes and enhances the clearance of abnormal protein such as beta- amyloid peptide and hyperphosphorlyated tau , the key pathological hallmarks of Alzheimer's disease.”
Bioactive effects of quercetin in the central nervous system: Focusing on the mechanisms of actions.“These observations indicate the ability of QUE to decrease tau protein hyperphosphorylation and thereby attenuate the associated neuropathology.”
“Western blotting results indicated that QUE significantly attenuated OA‑induced tau protein hyperphosphorylation at the Ser396, Ser199, Thr231 and Thr205 sites.”
“More importantly, pretreatment of neurons with Resveratrol or Quercetin significantly reduced the levels of caspase-3 cleaved- and hyperphosphorylated tau associated with HSV-1 infection.”
“Abstract It is reported that quercetin Que ) can prevent tau pathology and induce neuroprotection by improving cognitive and functional symptoms in the treatment of Alzheimer’s disease (AD).”
Brain delivery of quercetin-loaded exosomes improved cognitive function in AD mice by inhibiting phosphorylated tau-mediated neurofibrillary tangles“The ability of quercetin to inhibit tau fibrillization expands the paradigm for application of bioactive polyphenols.”
Nanobiocatalyst facilitated aglycosidic quercetin as a potent inhibitor of tau protein aggregation.
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