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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Quercetin and Tryptophan





Research Papers that Mention the Interaction

Quercetin induced mild stimulation of the tyrosinase activity and dihydroxyphenylalaminechrome tautomerase ( TRP‐2 ) expression but only at low concentrations (<20 μm) in B16F10 melanoma cells.
Phytotherapy research : PTR  •  2011  |  View Paper
Quercetin has been shown to induce the translocation of tryptophanyls and tyrosyls from membrane protein inner regions to their surface.
Ukrainskii biokhimicheskii zhurnal  •  1997  |  View Paper
Quercetin also increased the microenvironment hydrophilicity of tryptophan residues in glycosidase.
International journal of biological macromolecules  •  2021  |  View Paper
These findings, considered together, may indicate that quercetin restricts bacterial growth by promoting oxidative cellular stress, as well as by reducing the local L-tryptophan availability by activating the kynurenine pathway, thus contributing to our understanding of the molecular mechanism of the antimicrobial action of quercetin.
Biology  •  2020  |  View Paper