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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
supplement:
Quercetin
drug:
Trifluoperazine
Research Papers that Mention the Interaction
“The effect of quercetin was nullified by TMB8, a blocker of Ca2+ release from intracellular stores, and was strongly reduced by trifluoroperazine , an inhibitor of calmodulin actions, while it was unmodified by experimental manoeuvres able to alter cytosolic cAMP concentrations.”
Effect of the flavonol quercetin on ion transport in the isolated intestine of the eel, Anguilla anguilla.“The effect of quercetin was blocked by the calmodulin antagonists trifluoperazine and ophiobolin A and was diminished by a blocker of Ca2+ release from intracellular stores (TMB‐8), whereas the muscarinic receptor antagonist atropine was ineffective.”
“Studies on myofibrillar ATPase activity suggest that the stimulating effect of TFP is not identical in its underlying action with those of caffeine and quercetin , which are also known as Ca2+‐sensitizing drugs, having a similar eventual effect on tension development.”
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