Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 8 months ago

Possible Interaction: Quercetin and Trifluoperazine

supplement:

Quercetin

Research Papers that Mention the Interaction

The effect of quercetin was nullified by TMB8, a blocker of Ca2+ release from intracellular stores, and was strongly reduced by trifluoroperazine , an inhibitor of calmodulin actions, while it was unmodified by experimental manoeuvres able to alter cytosolic cAMP concentrations.
Comparative biochemistry and physiology. Toxicology & pharmacology : CBP  •  2006  |  View Paper
The effect of quercetin was blocked by the calmodulin antagonists trifluoperazine and ophiobolin A and was diminished by a blocker of Ca2+ release from intracellular stores (TMB‐8), whereas the muscarinic receptor antagonist atropine was ineffective.
Experimental physiology  •  2000  |  View Paper
Studies on myofibrillar ATPase activity suggest that the stimulating effect of TFP is not identical in its underlying action with those of caffeine and quercetin , which are also known as Ca2+‐sensitizing drugs, having a similar eventual effect on tension development.
The Journal of physiology  •  1988  |  View Paper