“The combination of quercetin , quercetin-3-glucuronide or 4'O-methyl-quercetin with tamsulosin decreased the phenylephrine sensitivity approximately 200-, 35- and 150-fold (n=6).”
“The combination of tamsulosin with quercetin or quercetin metabolites proved to be far more potent than the compounds in isolation.”
“The overlapping profile prompted us to investigate the pharmacodynamic interaction of quercetin with tamsulosin.”
“The strong pharmacodynamic interaction between the food supplement quercetin and tamsulosin underlines the potential of the impact of supplement-drug interactions that warrant more research.”