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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Quercetin and Talinolol



Research Papers that Mention the Interaction

The Cmax of talinolol in MDR1 3435 TT (382.4±149.1 vs 584.9±115.2 ng/ml, P=0.04) and MDR1 3435 CT (383.5±104.9 vs 554.6±80.6 ng/ml, P=0.01) individuals significantly decreased after the administration of quercetin.
The results also showed AUC0–48 h (5598.6±2202.1 vs 8229.4±1491.7 ng.h/ml, ….02) and AUC0–∞ (7110.0±3437.0 vs 12681.2±4828.2 ng.h/ml, P=0.01) of talinolol to be significantly decreased in … TT individuals administered of quercetin.
European Journal of Clinical Nutrition  •  2013  |  View Paper
Six of the investigated flavonoids reduced the secretory flux of talinolol across Caco-2 cells (IC50-values: hesperetin< quercetin <kaempferol<<spiraeoside<isoquercitrin<naringin).
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences  •  2005  |  View Paper