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Last Updated: 8 months ago

Possible Interaction: Quercetin and Substance P



Research Papers that Mention the Interaction

Quercetin also attenuated OVA induced MC degranulation, eosinophil number, substance P concentrations, and mRNA IL-4/TNF-α expression in the conjunctival tissue of AC models.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association  •  2019  |  View Paper
C48/80, a histamine promoter, and Substance P (a neuropeptide) EC50 was higher when combined with Quercetin compared to the EC50 of these compounds alone, suggesting that Quercetin could inhibit Mrgprx2‐induced pseudo‐allergic reaction.
International immunopharmacology  •  2019  |  View Paper
Oral administration of quercetin at more than 25 mg/kg for 5 days significantly inhibited the increase in SP , CGRP and NGF contents in nasal lavage fluids induced by TDI nasal challenge.
BMC Complementary and Alternative Medicine  •  2016  |  View Paper
These results suggest that quercetin potentiates plasma extravasation induced by substance P and bradykinin, and that this may result from inhibition of the degradative enzymes of these peptides.
Nutritional neuroscience  •  2003  |  View Paper
Further results suggested that the PE induced by SP in the dura mater was enhanced by pretreatment with quercetin , similar to that observed with selective peptidase inhibitors.
Phytotherapy research : PTR  •  2002  |  View Paper
The present study demonstrates that quercetin potentiates the PE induced by substance P in the urinary bladder.
Phytotherapy research : PTR  •  2001  |  View Paper
Results showed that Quercetin at 25 mg/kg and 50 mg/kg could significantly (p < .05) increase the intestinal transit rate, motilin, gastrin, substance P levels, and concentration of short‐chain fatty acids (SCFAs), reduce the somatostatin levels, and improve the gastrointestinal peristalsis of rats.
Food science & nutrition  •  2021  |  View Paper