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Last Updated: 8 months ago

Possible Interaction: Quercetin and Sorafenib

supplement:

Quercetin

Research Papers that Mention the Interaction

In conclusion, maintenance of effective anticancer activity of lower doses of sorafenib against thyroid cancer cells may be obtained by the co-administration of quercetin.
In this work, we investigated the effects of coadministration of quercetin and sorafenib on the proliferation, adhesion and migration properties of two different papillary thyroid cancer cell lines, to test the validity of this association to maintain the anticancer effects of sorafenib with lower dosage.
K1 and BCPAP cells treated with sorafenib 0.1 μM and quercetin 25 μM for 24 h showed a decrease in the cell proliferation rate (~70% vs untreated cells vs. ~30% reduction of sorafenib alone).
Endocrine  •  2019  |  View Paper
The occurrence of synergy when sorafenib and quercetin were added simultaneously to HCC cell lines was noticed.
Nutrition and cancer  •  2016  |  View Paper
Additional incubation with quercetin potentiated the pro-apoptotic properties of sorafenib.
Neurotoxicity Research  •  2013  |  View Paper