Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 8 months ago

Possible Interaction: Quercetin and Simvastatin

supplement:

Quercetin

Research Papers that Mention the Interaction

However, pretreatment with quercetin and simvastatin treatment attenuated the damage caused by hyperlipidemia compared with the hyperlipidemic group (P<0.05).
Pretreatment with quercetin and simvastatin treatment in the hyperlipidemic groups significantly (P<0.05) increased AChE activity compared with the hyperlipidemic group.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  •  2017  |  View Paper
Hyperlipidemic rats when receiving pretreatment with quercetin and treatment with simvastatin showed decreased levels of ATP and ADP when compared to the untreated hyperlipidemic group.
Molecular and Cellular Biochemistry  •  2017  |  View Paper
However, there was a trend towards a reduction of the maximum plasma concentration (C(max)) of simvastatin when quercetin was administered concomitantly (P=0.06).
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences  •  2009  |  View Paper
The flavonoid quercetin inhibited Hsp27 induction and abrogated simvastatin-mediated neuroprotection.
Neurobiology of Disease  •  2006  |  View Paper