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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Quercetin and Ritonavir



Research Papers that Mention the Interaction

Quercetin showed the strongest effect by improving the intracellular accumulation of ritonavir by 76.9 %.
quercetin in the co-administration group and in … plasma concentration-time curve (AUC0–t) of ritonavir by 42.2 % (p < 0.05) and 53.5 % (p < 0.01), and decreased the peak plasma … < 0.05) and 45.8 % (p < 0.01), respectively, compared to the control group (ritonavir alone).
Acta pharmaceutica  •  2016  |  View Paper
In vitro studies from our laboratory suggest that short-term exposure with pure herbal agents such as hypericin, kaempferol and quercetin or extract of SJW resulted in higher uptake or influx of ritonavir and erythromycin.
Life sciences  •  2006  |  View Paper
Quercetin , hypericin, and kaempferol exhibited a remarkable inhibition of P-gp–mediated efflux of ritonavir by increasing its cellular uptake in these models.
There was a significant decrease in the Apical to Basal/Basal to Apical (AP-BL/BL-AP) transport ratio of ritonavir in presence of hypericin, kaempferol, and quercetin.
American journal of therapeutics  •  2004  |  View Paper