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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Quercetin and Ribavirin



Research Papers that Mention the Interaction

Because they act on different enzyme targets and arrest the cell cycle at different phases, we tested the hypothesis that ribavirin and quercetin might be synergistic in growth inhibition and cytotoxicity.
Synergistic action was also obtained in OVCAR-5 cells in clonogenic assay when ribavirin was combined with quercetin in the sequence described above.
The mechanism of action is provided, in part at least, by the synergistic reduction of signal transduction (IP3 concentration) by ribavirin and quercetin.
When quercetin was added 24 h after ribavirin , synergistic antiproliferative action was observed in both myeloma 8,226 and OVCAR-5 cells.
Oncology research  •  1999  |  View Paper