supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
supplement:
Quercetin
drug:
Quetiapine
Research Papers that Mention the Interaction
“All the animals pre-treated with QCN , succumbed to death within 3–5 min of intravenous dosing of QTE (1 mg/kg).”
“Caution is advised for concomitant use of QCN rich dietary supplements with QTE.”
“The brain to plasma ratio of QTE increased upon QCN pre-treatment (2.6 vs 7.7), which could be attributed to P-glycoprotein inhibition at the blood–brain barrier by QCN.”
“The current set of studies indicated that serious herb–drug interaction between QCN and QTE might occur when they are co-administered.”
“The results showed a significant (p < 0.05) increase in exposure of QTE (peroral dosed) in the animals pre-treated with QCN as compared to the control group.”
“The studies in rat liver S9 fraction indicated that QCN could increase the metabolic stability of QTE by inhibiting the activity of CYP enzymes.”
Impact of quercetin on pharmacokinetics of quetiapine: insights from in-vivo studies in wistar rats
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback