Possible Interaction: Quercetin and Polyphenols

“In practice, diets as Mediterranean and the "French paradox" phenomenon, the light and moderate red wine consumption, supplementation with polyphenols as resveratrol or quercetin , and also experimental and clinical trials applying the mentioned have coincided in the antihypertensive effect of polyphenols , either in prevention or in therapy.”

“The use of quercetin and curcumin combination potentiates individual apoptotic effects of the polyphenols and reduces their effective dose thereby preventing potential toxic effects on normal cells.”

“In the present study we examined the inhibitory effect of the dietary polyphenols quercetin and resveratrol on EST activity, i.e. 17beta-estradiol (E2) sulfation.”

“At micromolar concentrations, five polyphenols , namely quercetin, butein, tannic acid, 2'-hydroxychalcone and morin, inhibited the efflux of CMB significantly; an inhibition of 40% was observed with 10 microM quercetin.”

“An improved general condition is observed after treatment with RES and QRC ; this explains the antioxidant and antiapoptotic effects of polyphenols.”

“OH production in the NADPH system, measured by formaldehyde production, was decreased by myricetin, fisetin and quercetin , but increased by kaempferol, morin and trans-resveratrol, indicating that z.rad;OH played a minor role in LP, which all of these PP inhibited.”