Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago

Possible Interaction: Quercetin and Meropenem

supplement:

Quercetin

Research Papers that Mention the Interaction

i) Virtual superimposition of quercetin onto meropenem , (ii) proximity of quercetin to attacking nucleophile and (iii) involvement of same amino acids that stabilize both meropenem and quercetin – indicated competition between quercetin and meropenem for ligand binding.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica  •  2019  |  View Paper
Hence, it would be important to investigate bactericidal and synergistic interaction of quercetin with meropenem and elucidate effects of quercetin alone and quercetin-meropenem combination on blaNDM, blaVIM,acrB, ompC, ompF, ompk35 and ompk36 expressions, cellular morphology and cell-wall/membrane integrity.
Quercetin exhibited bactericidal and synergistic activity with meropenem.
Microbial pathogenesis  •  2020  |  View Paper