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Last Updated: 8 months ago

Possible Interaction: Quercetin and Meropenem

supplement:

Quercetin

Research Papers that Mention the Interaction

i) Virtual superimposition of quercetin onto meropenem , (ii) proximity of quercetin to attacking nucleophile and (iii) involvement of same amino acids that stabilize both meropenem and quercetin – indicated competition between quercetin and meropenem for ligand binding.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica  •  2019  |  View Paper
Hence, it would be important to investigate bactericidal and synergistic interaction of quercetin with meropenem and elucidate effects of quercetin alone and quercetin-meropenem combination on blaNDM, blaVIM,acrB, ompC, ompF, ompk35 and ompk36 expressions, cellular morphology and cell-wall/membrane integrity.
Quercetin exhibited bactericidal and synergistic activity with meropenem.
Microbial pathogenesis  •  2020  |  View Paper