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Last Updated: 8 months ago

Possible Interaction: Quercetin and Iron, Dietary

supplement:

Quercetin

supplement:

Iron, Dietary

Research Papers that Mention the Interaction

Quercetin attenuated the abnormity induced by ethanol and/or iron.
The Journal of nutritional biochemistry  •  2014  |  View Paper
In this study, HUVECs was treated with 50 μM … 20 μM Que for 48 h. We found that Que attenuated the … by iron , as evidenced by decreased ROS generation, increased DDAHⅡexpression and activity, reduced ADMA level, … content and p-eNOS/eNOS ratio, and eventually caused a decrease in apoptosis.
European journal of pharmacology  •  2019  |  View Paper
Quercetin , rutin and (+)catechin exhibited strong antioxidant properties toward Fe , but this effect was decreased with respect to Zn ions.
PloS one  •  2016  |  View Paper
Consistent with this, cellular induction of HIF-1α by quercetin was abolished by pretreatment with iron.
HPH inhibition by quercetin was neutralized significantly by an elevated dose of iron.
Molecular Pharmacology  •  2007  |  View Paper
Our data demonstrate that quercetin depletes intracellular calcein-chelatable iron and that supplying additional iron from extracellular or intracellular pools abrogates the induction of HIF-1alpha by quercetin.
We propose that quercetin stabilises HIF-1alpha and inhibits cell proliferation predominantly by decreasing the concentration of intracellular iron through chelation.
Free radical research  •  2007  |  View Paper
Supplementation with quercetin significantly decreased liver Fe , V, and Se content, which was more noticeable in the Wistar rats than in the Z rats.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements  •  2020  |  View Paper
Meanwhile, quercetin lowered the iron level particularly in the islet in T2DM mice.
Nutrients  •  2020  |  View Paper
Besides, quercetin decreased malondialdehyde levels and histological damages in the liver and kidney of Fe group as compared with sham, DMSO and Quer groups.
General physiology and biophysics  •  2019  |  View Paper
In addition, quercetin upregulated Nrf2/HO-1 expression and modulated the labile iron pool in infected macrophages, culminating in a depletion of available iron for L. braziliensis replication.
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie  •  2019  |  View Paper
These findings show that QCT has a dual effect; at low doses it ameliorates the oxidative damage produced by iron , and it is genotoxic and cytotoxic at a higher dose.
Frontiers in bioscience  •  2017  |  View Paper
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