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Last Updated: 8 months ago

Possible Interaction: Quercetin and Gemcitabine

supplement:

Quercetin

Research Papers that Mention the Interaction

Quercetin , curcumin, and resveratrol have additive effect with gemcitabine to T24‐GCB cells.
The Kaohsiung journal of medical sciences  •  2020  |  View Paper
GEM treatment, in combination with quercetin , resulted in increased anticancer effects compared with GEM alone.
Anti-cancer drugs  •  2020  |  View Paper
For example, the combination of gemcitabine (GMC) with quercetin (QCT) showed a synergistic effect in inhibiting the migration of pancreatic cancer cells.
Journal of cellular physiology  •  2019  |  View Paper
Notably, quercetin showed a dramatic effect similar to RAGE silencing that effectively attenuated RAGE expression to facilitate cell cycle arrest, autophagy, apoptosis, and GEM chemosensitivity in MIA Paca-2 GEMR cells, suggesting that an additional reaction occurred under combined quercetin and GEM treatment.
Journal of food and drug analysis  •  2019  |  View Paper
Combination treatment with quercetin and gemcitabine downregulated HSP70 expression more prominently than treatment with quercetin or gemcitabine alone.
Clinical lung cancer  •  2015  |  View Paper
Targeting &bgr;-catenin using quercetin combined with gemcitabine may be a treatment strategy to improve prognosis in patients with pancreatic cancer.
The combination of quercetin and gemcitabine can reduce tumor growth and decrease drug resistance in pancreatic cancer.
Pancreas  •  2015  |  View Paper
A combination of gemcitabine and quercetin decreased the viability of both cell lines in a dose-dependent manner, which was more pronounced than gemcitabine treatment alone.
Conclusions Modulation of HSP 70 expression with quercetin enhanced the chemoresponsiveness of PCCs to gemcitabine.
Gut and liver  •  2013  |  View Paper