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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Quercetin
drug:
Gemcitabine
Research Papers that Mention the Interaction
“ Quercetin , curcumin, and resveratrol have additive effect with gemcitabine to T24‐GCB cells.”
Decreased drug resistance of bladder cancer using phytochemicals treatment“ GEM treatment, in combination with quercetin , resulted in increased anticancer effects compared with GEM alone.”
“For example, the combination of gemcitabine (GMC) with quercetin (QCT) showed a synergistic effect in inhibiting the migration of pancreatic cancer cells.”
“Notably, quercetin showed a dramatic effect similar to RAGE silencing that effectively attenuated RAGE expression to facilitate cell cycle arrest, autophagy, apoptosis, and GEM chemosensitivity in MIA Paca-2 GEMR cells, suggesting that an additional reaction occurred under combined quercetin and GEM treatment.”
“Combination treatment with quercetin and gemcitabine downregulated HSP70 expression more prominently than treatment with quercetin or gemcitabine alone.”
“Targeting &bgr;-catenin using quercetin combined with gemcitabine may be a treatment strategy to improve prognosis in patients with pancreatic cancer.”
“The combination of quercetin and gemcitabine can reduce tumor growth and decrease drug resistance in pancreatic cancer.”
“A combination of gemcitabine and quercetin decreased the viability of both cell lines in a dose-dependent manner, which was more pronounced than gemcitabine treatment alone.”
“Conclusions Modulation of HSP 70 expression with quercetin enhanced the chemoresponsiveness of PCCs to gemcitabine.”
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