Possible Interaction: Quercetin and Calcium Supplement

“Current results indicate that quercetin decreases proliferative properties and increases programmed cell death, in addition to altering the cell cycle, mitochondrial depolarization, level of reactive oxygen species, and concentration of cytoplasmic calcium in both cells.”

“It seems that the uterolytic activity of reviewed flavonoids such as naringenin, kaempferol and quercetin , especially in a calcium free solution , was via these inhibitory pathways.”

“ Quercetin caused significant depletion of cytosolic calcium levels and decreased calcium uptake from the intracellular stores.”

“Results: We report that quercetin inhibits collagen‐stimulated whole cell protein tyrosine phosphorylation and intracellular mobilization of calcium , in a concentration‐dependent manner.”

“Furthermore, the induction of HO-1 by quercetin suppressed the influx of calcium ions , a known trigger of IL-2 production.”

“It was found that QE treatment increased insulin, calcium , and magnesium levels.”

“ Quercetin increased the calcium sensitivity of the Ca2+ATPase like that observed with phosphorylation of phospholamban or treatment with monoclonal antibody 1D11.”

“ Quercetin also inhibited intestinal contraction induced by different concentrations of calcium , shifting the contraction curve to the right showing a clear calcium-antagonistic effect.”

“The inhibitory effects of nafazatrom and quercetin were antagonized by Ca2+ (2.5 mM) or Bay K 8644 (1 microM), a calcium channel activator.”

“ Quercetin (3, 3′, 4′, 5, 7‐pentahydroxyflavone) has been shown to inhibit a variety of enzymes including the calcium‐ and phospholipid‐dependent protein kinase (protein kinase C) in vivo and in vitro.”