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Last Updated: 2 years ago

Possible Interaction: Quercetin and Buthionine Sulfoximine

Research Papers that Mention the Interaction

Quercetin concentration-dependently (EC50: 30-40 microM) reduced oxidative injury of BSO to all cell types, and was also effective when first added after BSO washout.
Free radical biology & medicine  •  1997  |  View Paper
We found that treating cells with buthionine sulfoximine to deplete cellular GSH levels significantly reduced the capacity of quercetin to inhibit lipopolysaccharide (LPS)-induced oxidant production.
Redox biology  •  2016  |  View Paper
Quercetin significantly ameliorated free radical-induced neuronal injury caused by buthionine sulfoximine , sodium nitroprusside, ZnCl(2), and FeCl(2).
Biological & pharmaceutical bulletin  •  2003  |  View Paper
Primary cortical neuronal cells derived from mouse embryos were preincubated with ACE or QCT for … and exposed to L-buthionine sulfoximine for 4~24 h. We found that ACE and QCT significantly decreased neuronal death and the ROS … by L-buthionine-S, R-sulfoximine ( BSO ) in a …-dependent manner.
Oxidative medicine and cellular longevity  •  2016  |  View Paper