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Last Updated: 8 months ago

Possible Interaction: Quercetin and Bortezomib



Research Papers that Mention the Interaction

Moreover, quercetin induced a prosurvival autophagy in these cells and increased the cytotoxic effect of bortezomib , a proteasomal inhibitor, against them.
The Journal of nutritional biochemistry  •  2017  |  View Paper
This inhibitory effect was associated with chemical reactions between quercetin and the boronic acid group, -RB(OH)2, in bortezomib.
Blood  •  2008  |  View Paper
A DNA ladder assay also confirmed the inhibitory effect of quercetin on the apoptosis-inducing effect of bortezomib.
Quantitation of cell viability also indicated that quercetin interfered with the cytotoxic effects of bortezomib.
Unexpectedly, such morphological changes were not observed in cells treated with 20 µM quercetin alone, nor in cells treated with bortezomib + quercetin, indicating that quercetin inhibited the cytotoxic effects of bortezomib.
Molecular medicine reports  •  2010  |  View Paper