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Last Updated: 8 months ago

Possible Interaction: Quercetin and Aldesleukin

supplement:

Quercetin

Research Papers that Mention the Interaction

Furthermore, catechin, epigallocatechin gallate (EGCG), epicatechin (EC), luteolin, chrysin, quercetin , and galangin increased IL-2 secretion while EGC, apigenin, and fisetin inhibited the secretion.
Archives of pharmacal research  •  2005  |  View Paper
Using semi-quantitative and real-time RT-PCR, we show that QC inhibits IL-2 gene expression in activated Jurkat cells.
Journal of biochemistry  •  2010  |  View Paper
Quercetin also suppressed transcription factor activation in 4 h-cultured cells and mRNA expression of chemokine in 12 h-cultured cells, which were increased by stem cell factor stimulation.
In vivo  •  2014  |  View Paper
Here, we studied the function of quercetin in Th cells and found that quercetin suppressed both IFNgamma and IL-2 production upon T cell receptor stimulation.
Taken together, quercetin is suggested to repress both IFNgamma and IL-2 cytokine production by independent mechanisms; T-bet-dependent IFNgamma suppression and IL-2R alpha-dependent IL-2 inhibition.
Biochemical pharmacology  •  2008  |  View Paper
The data show that QCT treatment leads to an obvious decrease of multiple inflammatory cytokines in transcript level, including interleukin (IL)-1α, IL-1β, IL-2 , IL-10, macrophage chemoattractant protein-1 (MCP-1), and cyclooxygenase-2 (COX-2) induced by LPS.
Front. Pharmacol.  •  2017  |  View Paper