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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
supplement:
Quercetin
drug:
Aldesleukin
Research Papers that Mention the Interaction
“Furthermore, catechin, epigallocatechin gallate (EGCG), epicatechin (EC), luteolin, chrysin, quercetin , and galangin increased IL-2 secretion while EGC, apigenin, and fisetin inhibited the secretion.”
Production of Cytokine and NO by RAW 264.7 Macrophages and PBMC In Vitro Incubation with Flavonoids“Using semi-quantitative and real-time RT-PCR, we show that QC inhibits IL-2 gene expression in activated Jurkat cells.”
“ Quercetin also suppressed transcription factor activation in 4 h-cultured cells and mRNA expression of chemokine in 12 h-cultured cells, which were increased by stem cell factor stimulation.”
Suppressive activity of quercetin on the production of eosinophil chemoattractants from eosinophils in vitro.“Here, we studied the function of quercetin in Th cells and found that quercetin suppressed both IFNgamma and IL-2 production upon T cell receptor stimulation.”
“Taken together, quercetin is suggested to repress both IFNgamma and IL-2 cytokine production by independent mechanisms; T-bet-dependent IFNgamma suppression and IL-2R alpha-dependent IL-2 inhibition.”
“The data show that QCT treatment leads to an obvious decrease of multiple inflammatory cytokines in transcript level, including interleukin (IL)-1α, IL-1β, IL-2 , IL-10, macrophage chemoattractant protein-1 (MCP-1), and cyclooxygenase-2 (COX-2) induced by LPS.”
Quercetin Inhibits LPS-Induced Inflammation and ox-LDL-Induced Lipid Deposition
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