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Discover Supplement-Drug Interactions
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Last Updated: 5 years ago
drug:
Pyruvic Acid
supplement:
Alpha-Ketoglutarate
Research Papers that Mention the Interaction
“On the decarboxylation of pyruvate, alpha-ketoglutarate , and branched-chain alpha-keto acids in intact mitochondria, those alpha-keto acids inhibited one another.”
Inhibition of glycine oxidation by pyruvate, alpha-ketoglutarate, and branched-chain alpha-keto acids in rat liver mitochondria: presence of interaction between the glycine cleavage system and alpha-keto acid dehydrogenase complexes.“The incorporation of pyruvic acid into gradient agar cultures increased iridescent lysis, but the reduction of the iridescent lysis by 2-oxoglutarate was variable and unpredictable.”
A metabolic inquiry into the iridescent lysis of agar lawns of Pseudomonas aeruginosa strain 227.
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