“Pretreatment of slices with either the glial metabolism inhibitor, fluoroacetate (5 mM), or D‐serine (100 &mgr;M) diminished the pyrilamine‐ or cetirizine‐induced attenuation of the NMDAR‐mediated EPSCs.”
“Pretreatment with D‐serine again attenuated the pyrilamine‐induced suppression of LTP.”
“ Pyrilamine and cetirizine decreased the induction of LTP in the CA1.This effect was attenuated by pretreatment with D‐serine.”