Possible Interaction: Pyridoxamine and Vitamin B 6

“Reducing the pyridoxine content of the culture medium significantly increased the activity of pyridoxal kinase and pyridoxamine 5'-phosphate oxidase.”

“Ingestion of pyridoxine also greatly increased the amount of pyridoxal and pyridoxamine excreted.”

“This study demonstrated an inhibitory effect of PM on vasculogenesis in this EB model as well as PLP and PL, and suggests that suppression of EPC differentiation is at least in part responsible for the mechanism of the anti-angiogenesis effect of vitamin B(6).”

“ PLP disappearance was significantly inhibited by 1 micrometer pyridoxamine 5'-phosphate and 5 micrometers and 10 micrometers l-phenylalanine but not by 1 micrometer pyridoxamine.”

“The absorbance spectrum of pyridoxamine (pyridoxine)-5'-phosphate oxidase (EC 1.4.3.5) is altered upon the binding of pyridoxal 5'-phosphate or analogs with different substituents at position 4'.”

“We found a small increase of PN to a maximum of 13.5 ± 2.1 nmol/L; it was nearly undetectable … ~12 h. With a three daily dose of 67 mg PM we observed an increase and decline of plasma PM, PL , and PN concentrations after each PM intake.”

“Our metabolite QTL analysis illustrated that different genetic factors may presumably regulate the accumulation of 4-pyridoxate and pyridoxamine in vitamin B6 metabolism.”

“ PL supplementation increased the levels of plant PN and PM significantly, but not that of PL, suggesting that efficient conversion pathways from PL to PN and PM are present in tobacco.”

“The anion-binding affinities of the pyridoxamine enzyme are higher than those for the pyridoxal enzyme in both supernatant and mitochondrial transminases.”