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Discover Supplement-Drug Interactions
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Last Updated: 2 years ago
drug:
Psychotropic Drugs
supplement:
Kava
Research Papers that Mention the Interaction
“ Kava (Piper methysticum) elicits dose‐dependent psychotropic effects and thus may potentially deleteriously affect cognitive performance.”
Neurocognitive effects of kava (Piper methysticum): a systematic review“Growing research indicates that kava most likely alters concentrations of coadministered psychotropics possibly by inhibiting cytochrome P450 enzymes.”
“In both cases, kava use may have affected the metabolism of the psychotropic medications , leading to serious side effects.”
“Two cases of patients seen on the psychiatric emergency and consult service who developed severe side effects from psychotropic medications in the context of kava use are presented.”
Toxic effects of psychotropics related to possible p450 enzyme inhibition by kava: report of 2 cases.
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