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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Prothionamide and Glutamic Acid

Research Papers that Mention the Interaction

Thionamides resemble the methyltetrazole-thiol leaving … of certain cephalosporin antibiotics, and both thionamides and cephalosporins have been found to inhibit the vitamin-K-dependent gamma-carboxylation of glutamic acid in vitro [8]: actually, PTU has been associated with hypoprothrombinemia [9], disseminated intravascular coagulation [10], and acute thrombocytopenic purpura [11].
Annals of Hematology  •  2007  |  View Paper