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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Prothionamide
supplement:
Glutamic Acid
Research Papers that Mention the Interaction
“Thionamides resemble the methyltetrazole-thiol leaving … of certain cephalosporin antibiotics, and both thionamides and cephalosporins have been found to inhibit the vitamin-K-dependent gamma-carboxylation of glutamic acid in vitro [8]: actually, PTU has been associated with hypoprothrombinemia [9], disseminated intravascular coagulation [10], and acute thrombocytopenic purpura [11].”
Long-term propylthiouracil use and acute myeloid leukemia: A case report and review of the literature
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