supp.ai
Discover Supplement-Drug Interactions
Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 3 years ago
drug:
Propranolol
supplement:
Digitalis
Research Papers that Mention the Interaction
“ Propranolol at a dose of 30 mg per day in combination with diuretics and digitalis decreased atrial rate of tachycardia and the cardiac size in both cases.”
Two cases of dilated cardiomyopathy associated with incessant supraventricular tachycardia who showed a favorable response to beta-blockade.“A patient with coarse atrial fibrillation and a rapid ventricular response developed periods of high grade atrioventricular block interpersed with periods of rapid ventricular conduction after the administration of digitalis and propranolol.”
“The attacks were controlled by the association of propranolol and digitalis which seems to be the optimal long-term therapy in such cases.”
“Three patients with arrhythmias due to digitalis intoxication showed a significant reduction of ventricular rate in response to propranolol.”
“Our results indicate that propranolol increases the sensitivity of Na+,K+-ATPase to inhibition by digitalis , and that stimulation of Na+,K+-ATPase in bovine myocardium is not mediated via an adrenergic mechanism.”
Digitalis‐Sensitive Na+,K+‐ATPase: Lack of a Direct Catecholamine‐Mediated Stimulation in Bovine Myocardial Tissue“ Propranolol did reduce the myocardial uptake of digoxin, but this was not considered of sufficient magnitude to be the main factor in suppressing arrhythmias induced by digitalis.”
“Beta-blocking doses of propranolol given to dogs bordering on digitalis toxicity but in normal sinus rhythm caused recurrence of sustained ventricular tachycardia.”
Help us improve supp.ai, we'd love to hear your feedback: Submit Feedback