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Discover Supplement-Drug Interactions

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Last Updated: 8 months ago

Possible Interaction: Propranolol and Digitalis

supplement:

Digitalis

Research Papers that Mention the Interaction

Propranolol at a dose of 30 mg per day in combination with diuretics and digitalis decreased atrial rate of tachycardia and the cardiac size in both cases.
Heart and vessels. Supplement  •  1990  |  View Paper
A patient with coarse atrial fibrillation and a rapid ventricular response developed periods of high grade atrioventricular block interpersed with periods of rapid ventricular conduction after the administration of digitalis and propranolol.
British heart journal  •  1979  |  View Paper
The attacks were controlled by the association of propranolol and digitalis which seems to be the optimal long-term therapy in such cases.
American heart journal  •  1976  |  View Paper
Three patients with arrhythmias due to digitalis intoxication showed a significant reduction of ventricular rate in response to propranolol.
The American journal of cardiology  •  1966  |  View Paper
Our results indicate that propranolol increases the sensitivity of Na+,K+-ATPase to inhibition by digitalis , and that stimulation of Na+,K+-ATPase in bovine myocardium is not mediated via an adrenergic mechanism.
Journal of cardiovascular pharmacology  •  1983  |  View Paper
Propranolol did reduce the myocardial uptake of digoxin, but this was not considered of sufficient magnitude to be the main factor in suppressing arrhythmias induced by digitalis.
International journal of clinical pharmacology and biopharmacy  •  1975  |  View Paper
Beta-blocking doses of propranolol given to dogs bordering on digitalis toxicity but in normal sinus rhythm caused recurrence of sustained ventricular tachycardia.
Circulation  •  1969  |  View Paper