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Last Updated: 3 years ago

Possible Interaction: Propranolol and Arachidonate

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drug:

Propranolol

supplement:

Arachidonate

Research Papers that Mention the Interaction

“Treatment of PMN with ethanol (an inhibitor of PLD‐mediated phosphatidic acid formation), propranolol (a phosphatidic acid phosphatase inhibitor), or 4‐bromophenacylbromide (a PLA2 inhibitor), each suppressed fMLP‐stimulated arachidonate release.”

Phospholipase D is involved in cytosolic phospholipase A2‐dependent selective release of arachidonic acid by fMLP‐stimulated rat neutrophils

FEBS letters • 1996 | View Paper

“In contrast, propranolol , which enhanced PA accumulation, significantly increased the arachidonate liberation.”

Enhancement of phospholipase A2 activation by phosphatidic acid endogenously formed through phospholipase D action in rat peritoneal mast cell

FEBS letters • 1993 | View Paper

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