Allen Institute for Artificial Intelligence
supp.ai logo
supp.ai

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 8 months ago

Possible Interaction: Propofol and Vitamin C

supplement:

Vitamin C

Research Papers that Mention the Interaction

Although ascorbic acid alone has no appreciable effect, the protective effect of propofol was enhanced by ascorbic acid.
These and other results suggest that propofol interacts with ascorbic acid , thereby exhibiting potent antioxidant activity in and around membranes as does alpha-tocopherol.
American journal of respiratory and critical care medicine  •  2002  |  View Paper
CONCLUSION Vi amin C ca n reduce the dose of pro pofol wi thout obviously affecting the anesthetic effect to reduce the incidence of drug tolerance and potential dose-related side effects of propofol.
Nan fang yi ke da xue xue bao = Journal of Southern Medical University  •  2015  |  View Paper
Conclusion Vitamin C can reduce the dosage of propofol in patients undergoing total knee replacement.
Journal of pain research  •  2021  |  View Paper
The addition of propofol (10 mg/ml) partially inhibited the decline in pH and ascorbic acid (0.05 mg/ml) completely inhibited it.
Anesthesiology  •  2002  |  View Paper