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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
Research Papers that Mention the Interaction
“In addition, propofol decreased tyrosine phosphorylation of protein phosphatase 2A at tyrosine 307, resulting in an increase in protein phosphatase 2A activity.”
Propofol Inhibits Phosphorylation of N-methyl-d-aspartate Receptor NR1 Subunits in Neurons“Results:Clinically relevant concentrations of thiopental, propofol , etomidate, isoflurane, sevoflurane, and desflurane induced a concentration-related increase in tyrosine phosphorylation.”
“ Propofol caused an increase (33 +/- 10%) in tyrosine phosphorylation, with maximum at 120 s, of the beta-subunit of the GABA(A)-receptor.”
“Crystallographic studies suggest that there is a direct interaction between propofol and the phenolic residue of a tyrosine in the channel.”
Mimicking anaesthetic-receptor interaction: a combined spectroscopic and computational study of propofol···phenol.
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