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Discover Supplement-Drug Interactions
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Last Updated: 3 years ago
drug:
Propofol
supplement:
Calcium Supplement
Research Papers that Mention the Interaction
“Although propofol (>50 μM) increased intracellular calcium in a dose-dependent manner in these cells, it was not influenced by the elimination of extracellular calcium.”
Propofol induces the elevation of intracellular calcium via morphological changes in intracellular organelles, including the endoplasmic reticulum and mitochondria.“Specifically, sodium, calcium and potassium currents in cardiac cells are suppressed by clinically relevant concentrations of propofol.”
“ Propofol could alleviate H/R-induced intracellular calcium accumulation and MMP loss by inhibiting calcineurin activity and FKBP12.6-RyR disassociation in a concentration-dependent manner.”
“The signaling pathways downstream from FPR1, involving calcium , AKT, and ERK1/2, were also competitively inhibited by propofol.”
“ Propofol decreased the concentration of intracellular calcium , whereas aminophylline caused increased mobilization of intracellular calcium in a concentration-dependent manner.”
“ Propofol further prevented the aminophylline-induced increase of intracellular calcium at clinically relevant concentrations.”
“ Propofol suppressed the lysophosphatidic acid-induced mobilization of intracellular calcium in a concentration-dependent manner.”
“Midazolam, propofol , and thiopental each attenuated (P < 0.05) both peak and sustained CCE , whereas ketamine, etomidate, morphine, and fentanyl had no effect on CCE.”
“Midazolam, propofol , and thiopental each attenuated CCE , whereas ketamine, etomidate, morphine, and fentanyl had no effect on CCE.”
“Activation with propofol resulted in sustained increased intracellular calcium concentrations concomitant with actin reorganization and induction of migration in MDA‐MB‐468 cells.”
“In addition, propofol induced intracellular calcium concentration, and activated CaMKII as well as PKCβ.”
Angiotensin II-mediated suppression of synaptic proteins in mouse hippocampal neuronal HT22 cell was inhibited by propofol: role of calcium signaling pathway“Levels of intracellular calcium were significantly attenuated in cultured VSMC treated with propofol (10mM).”
“Background: The authors have previously demonstrated that propofol attenuates capacitative calcium entry ( CCE ) via the protein kinase C signaling pathway in pulmonary artery smooth muscle cells (PVSMCs).”
“ Propofol attenuates CCE via a TK-independent mechanism.”
“Thiopental, midazolam, ketamine, and propofol each attenuated both peak and sustained CCE.”
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