Allen Institute for Artificial Intelligence logo

Discover Supplement-Drug Interactions

Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. The tool is not a substitute for the care provided… (more)
Last Updated: 8 months ago

Possible Interaction: Propofol and Calcium Supplement

Research Papers that Mention the Interaction

Although propofol (>50 μM) increased intracellular calcium in a dose-dependent manner in these cells, it was not influenced by the elimination of extracellular calcium.
European journal of pharmacology  •  2020  |  View Paper
Specifically, sodium, calcium and potassium currents in cardiac cells are suppressed by clinically relevant concentrations of propofol.
Acta Pharmacologica Sinica  •  2011  |  View Paper
Propofol could alleviate H/R-induced intracellular calcium accumulation and MMP loss by inhibiting calcineurin activity and FKBP12.6-RyR disassociation in a concentration-dependent manner.
Oxidative medicine and cellular longevity  •  2018  |  View Paper
The signaling pathways downstream from FPR1, involving calcium , AKT, and ERK1/2, were also competitively inhibited by propofol.
The Journal of Immunology  •  2013  |  View Paper
Propofol decreased the concentration of intracellular calcium , whereas aminophylline caused increased mobilization of intracellular calcium in a concentration-dependent manner.
Propofol further prevented the aminophylline-induced increase of intracellular calcium at clinically relevant concentrations.
Propofol suppressed the lysophosphatidic acid-induced mobilization of intracellular calcium in a concentration-dependent manner.
Journal of Korean medical science  •  2010  |  View Paper
Midazolam, propofol , and thiopental each attenuated (P < 0.05) both peak and sustained CCE , whereas ketamine, etomidate, morphine, and fentanyl had no effect on CCE.
Midazolam, propofol , and thiopental each attenuated CCE , whereas ketamine, etomidate, morphine, and fentanyl had no effect on CCE.
American journal of physiology. Lung cellular and molecular physiology  •  2008  |  View Paper
Activation with propofol resulted in sustained increased intracellular calcium concentrations concomitant with actin reorganization and induction of migration in MDA‐MB‐468 cells.
European journal of anaesthesiology  •  2005  |  View Paper
In addition, propofol induced intracellular calcium concentration, and activated CaMKII as well as PKCβ.
Journal of Anesthesia  •  2018  |  View Paper
Levels of intracellular calcium were significantly attenuated in cultured VSMC treated with propofol (10mM).
Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine  •  2010  |  View Paper
Background: The authors have previously demonstrated that propofol attenuates capacitative calcium entry ( CCE ) via the protein kinase C signaling pathway in pulmonary artery smooth muscle cells (PVSMCs).
Propofol attenuates CCE via a TK-independent mechanism.
Thiopental, midazolam, ketamine, and propofol each attenuated both peak and sustained CCE.
Anesthesiology  •  2006  |  View Paper
Show More